Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0314877
PubChem CID
Molecular Formula
C6H8ClN7O
Molecular Weight
229.631 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
XSDQTOBWRPYKKA-UHFFFAOYSA-N
InChI
InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)
IUPAC Name
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

15 15 0 0 0 0 0 0 0 0999 V2000
-4.5523 1.9148 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-3.6824 0.6928 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-4.3057 -0...

Experimental Data

Activity Data

Target Ion Channel
Sodium channel protein type 5 subunit alpha
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 781 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not specified
Temperature
Room Temperature
Test Method
Fluorometric Imaging Plate Reader (FLIPR) assay
Test Species
canine bronchial epithelial (CBE) cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

DOI
N/A (Not available)
URL
N/A (Not available)
PMID
N/A (Not available)
Patent
US10246425

Computed Properties

Heavy Atom Count
15
Rotatable Bonds
1
logP
-1.0823
Complexity
55.2471
TPSA (Ų)
156.79
H-Bond Donors
5
H-Bond Acceptors
6
Ring Count
1
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